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Updated: Sep 9, 2025

Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions
06:50

Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions

Published on: January 26, 2024

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Alphappimi: PPI-モジュレーターの相互作用を予測するための包括的なディープラーニングフレームワーク

Dayan Liu1,2, Tao Song1,2, Shuang Wang1,2

  • 1College of Computer Science and Technology, China University of Petroleum (East China), Qingdao, 266580, Shandong, China.

Journal of cheminformatics
|August 29, 2025
PubMed
まとめ

AlphaPPIMIは,タンパク質とタンパク質の相互作用 (PPI) を標的とする変調子を正確に予測する新しいディープラーニングフレームワークです. この計算ツールは,潜在的な薬剤候補を優先順位付けすることで,標的型PPI治療法を発見するのに役立ちます.

キーワード:
ディープラーニングドメインの適応薬物の発見インターフェースターゲティングタンパク質同士の相互作用

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Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease09:38

Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease

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