青少年における結核治療を支援するデジタルアデバーンス技術の利用
A M Schraufnagel1, R Crowder2, P Wambi3
1Division of Pulmonary and Critical Care Medicine, San Francisco General Hospital, University of California San Francisco, San Francisco, CA, USA.
まとめ
99DOTSのようなデジタルアデバーンス技術 (DAT) は,青少年における結核 (TB) 治療結果の改善に寄与しています. この研究では,99DOTSの使用は,この年齢層における治療成功率の上昇と,フォローアップへの損失の減少と関連していることが判明しました.
科学分野:
- 公衆衛生
- 感染症
- 青少年 の 健康
背景:
- 結核 (TB) を 患う 青少年 は,治療 を 終える とき に 独特 な 挑戦 を 経験 し ます.
- デジタルアデランス技術 (DAT) は,結核治療へのアデランスを監視するための潜在的な解決策を提供します.
- 99DOTSという低コストのDATは,青少年における結核治療結果への影響について調査されました.
研究 の 目的:
- 肺結核 (PTB) の青少年における治療結果の改善における99DOTSの有効性を評価する.
- 青少年における結核治療の順守と成功率に対する99DOTSベースの介入の受け入れと影響を評価する.
主な方法:
- 割り切れた時間シリーズ (ITS) の分析が行われました.
- この研究では,ウガンダの30の保健施設で薬物に敏感なPTBの治療を開始した若者を対象とした.
- ITSモデルは,99DOTSの導入前と後に結核治療の結果の変化とフォローアップへの損失を分析するために使用されました.
主要な成果:
- 99DOTSの摂取量が高く,介入後の若者の78. 4%が登録された.
- 調整した分析では,治療成功率の有意な増加を示した (PR1.18,95%CI1. 08-1. 28).
- 追跡への損失の有意な減少が観察された (PR 0. 93,95%CI 0. 88- 0. 98).
結論:
- 99DOTSは,結核の青少年の間で高い受容性と有効性を示した.
- 99DOTSの使用は,青少年における結核治療の改善と有意に関連していました.
- DAT,特に99DOTSは結核治療の成功を高める 有望な青少年特有の戦略です.
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