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Updated: Sep 9, 2025

Evaluation of the Storage Stability of Extracellular Vesicles
11:31

Evaluation of the Storage Stability of Extracellular Vesicles

Published on: May 22, 2019

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第2回ヨーロッパにおける膀研究のためのMOBILITY (MOVE) シンポジウム-2024に関する報告

Dorival Mendes Rodrigues-Junior1, Michaela Kocholata2, Marilena E Lekka3

  • 1Department of Medical Biochemistry and Microbiology, Science for Life Laboratory, Biomedical Center, Uppsala University, Sweden.

FEBS open bio
|August 30, 2025
PubMed
まとめ

第2回ヨーロッパにおける膀研究のためのモビリティ (MOVE) シンポジウムは,細胞外膀 (EV) 研究を進めるために280人以上の専門家を招集した. このイベントは,EVの生体生成,アプリケーション,技術における欧州全体の協力を促進し,イノベーションを共有しました.

キーワード:
バイオマーカーエクソソーム細胞外膀細胞間通信マイクロベシクル研究者への移動

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The Movement of Organelles and Vesicles

In eukaryotic cells,  cytoskeletal filaments such as actin, microtubules, and intermediate filaments form a mesh-like cytoskeletal network. These filaments serve as tracks for transporting cellular cargo. Specialized motor proteins use the chemical energy stored in adenosine triphosphate (ATP) for this transport. During interphase, microtubules are polarized, with the plus-end towards the cell periphery and the minus-end towards the cell center. Two microtubule-associated motor proteins,...
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With the help of motor proteins such...
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Intraluminal vesicles (ILVs) are small vesicles 50-80 nm in diameter formed during the maturation of early endosomes. A specialized endosome containing numerous ILVs is called a multivesicular body (MVB). ILVs contain internalized molecules such as antigens, nucleic acids, proteins, and metabolites. Some of these molecules are released from the MVBs inside exosomes and are transported to other cells. Other MVBs contain molecules that are retained in the ILVs and are later degraded within the...
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Secretory vesicles, also known as dense core vesicles (DCVs), are membrane-bound vesicles that transport secretory proteins, such as hormones or neurotransmitters. Regulated secretory vesicles transport proteins from the trans-Golgi network to the exterior of the cell. Proteins present in regulated secretory vesicles are required to be rapidly exocytosed in large amounts upon a specific stimulus.
Various proteins regulate the aggregation of molecules inside the secretory vesicles. Chromogranins...
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