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Updated: Sep 9, 2025

Adoptive Transfer of IL-33-Stimulated Macrophages into Bleomycin-Induced Mouse Models to Study Their Effect on Idiopathic Pulmonary Fibrosis In Vivo
06:29

Adoptive Transfer of IL-33-Stimulated Macrophages into Bleomycin-Induced Mouse Models to Study Their Effect on Idiopathic Pulmonary Fibrosis In Vivo

Published on: May 5, 2023

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トランスクリプション中間因子1ガマは,肺炎と線維症を,アルベオラ型2細胞,線維芽細胞,およびマクロファージを通じて予防する

Dodam Moon1, Hyomin Park1, Tae Yoon Kim1

  • 1Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 03080, Republic of Korea.

Molecular therapy : the journal of the American Society of Gene Therapy
|August 30, 2025
PubMed
まとめ

トランスクリプション中間因子1ガンマ (TIF1γ) は,肺線維症 (PF) の治療の可能性を示しています. このタンパク質は肺細胞とマクロファージの主要な線維経路を阻害し,線維症を軽減し,臨床前モデルで肺機能を改善します.

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Oropharyngeal Administration of Bleomycin in the Murine Model of Pulmonary Fibrosis06:03

Oropharyngeal Administration of Bleomycin in the Murine Model of Pulmonary Fibrosis

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