関連する実験動画

Updated: Sep 9, 2025

Analysis of HBV-Specific CD4 T-cell Responses and Identification of HLA-DR-Restricted CD4 T-Cell Epitopes Based on a Peptide Matrix
10:37

Analysis of HBV-Specific CD4 T-cell Responses and Identification of HLA-DR-Restricted CD4 T-Cell Epitopes Based on a Peptide Matrix

Published on: October 20, 2021

3.0K

周周および肝内B細胞の単細胞プロファイリングにより,慢性HBV感染における抗ウイルス能力に関連したCCR7+サブセットと変化した反応が明らかになった

Shihong Zhong1, Zhaofeng Zeng1, Zihan Jin1

  • 1Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, State Key Laboratory of Organ Failure Research, Key Laboratory of Infectious Diseases Research in South China (Southern Medical University), Ministry of Education, Guangdong Provincial Key Laboratory for Prevention and Control of Major Liver Diseases, Guangdong Provincial Clinical Research Center for Viral Hepatitis, Guangdong Institute of Hepatology, Guangdong Provincial Research Center for Liver Fibrosis Engineering and Technology, Guangzhou, China.

Journal of medical virology
|August 30, 2025
PubMed
まとめ

慢性的なB型肝炎ウイルス (HBV) 感染症のB細胞は,シグナル伝達が低下し,抗ウイルスサイトカインの産生が減少した機能を示します. 肝臓内B細胞はより活発で,CCR7+B細胞は有効な抗HBV治療の鍵となる可能性があります.

キーワード:
B セルBCRシグナリングCCR7+B細胞についてB型肝炎ウイルススクRNA-seq

さらに関連する動画

Stem Cell-Derived Viral Ag-Specific T Lymphocytes Suppress HBV Replication in Mice07:25

Stem Cell-Derived Viral Ag-Specific T Lymphocytes Suppress HBV Replication in Mice

Published on: September 25, 2019

6.9K
Development of a Hepatitis B Virus Reporter System to Monitor the Early Stages of the Replication Cycle09:35

Development of a Hepatitis B Virus Reporter System to Monitor the Early Stages of the Replication Cycle

Published on: February 1, 2017

13.4K

関連する概念動画

B Cell Activation and Differentiation01:24

B Cell Activation and Differentiation

The adaptive immune response, a sophisticated defense mechanism, relies on the activation and differentiation of B lymphocytes, or B cells. These processes enable our bodies to mount a tailored response against specific pathogens such as bacteria, free virus particles, toxins, and parasites.
When naive B cells encounter a specific antigen that can bind to the B cell receptor (BCR) on their surface, they undergo sensitization to respond to the antigen's presence. Sensitization begins with...
5.5K