バイオミメティック・デュアル・エンジン・ナノ破壊機は,細胞外マトリックスを退化させ,TAM2をハイジャックし,HCCにおける深い免疫浸透を解き放つ

Jianwei Yang1,2, Zhongsheng Xu1,2, Haiyan Lan2

  • 1Department of Radiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.

まとめ

この研究では,腫瘍関連ファイブロブラストとマクロファージを再プログラムすることで,肝細胞癌 (HCC) を標的とする新しいナノ医薬品であるZHL@CMを紹介しています. このアプローチにより 薬の浸透が促進され 癌に対する全身免疫反応が強化されます

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