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Updated: Sep 9, 2025

Live Cell Calcium Imaging Combined with siRNA Mediated Gene Silencing Identifies Ca2+ Leak Channels in the ER Membrane and their Regulatory Mechanisms
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女性における血清カルシジオールとカルシトリオール濃度の不一致は,個体間の遺伝的差異によって引き起こされる

Elizabeth K Hutchins1, Changran Niu2, Jing Xue1

  • 1Department of Genetics, University of North Carolina, Chapel Hill, NC.

Endocrinology
|August 30, 2025
PubMed
まとめ

遺伝的差異は,カルシジオール濃度だけでなく,カルシジオールの生成とシグナル伝達に影響を与えることで,ビタミンD欠乏症 (VDI) を引き起こします. これは,ビタミンDの代謝と様々な集団に対する潜在的な臨床的影響に関する新しい洞察を明らかにします.

キーワード:
カルシトリオールコラボレーション クロスマウスモデル栄養遺伝学精密栄養ビタミンD

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