自宅での矯正性低血圧および高血圧の自己測定 - 罹患率および動脈硬化および動脈硬化との関連
F Frey1, P Af Geijerstam2, F Iredahl2,3
1Department of Internal Medicine and Department of Health, Medicine and Caring Sciences, Linkoping University, Norrköping, Sweden.
American journal of hypertension
|August 30, 2025
まとめ
自宅で測定された正静性低血圧と高血圧は,動脈硬化マーカーと関連しています. 家庭での静脈低血圧は 動脈の硬化にも関係しており,家庭での血圧の監視の重要性を強調しています.
科学分野:
- 心臓病科
- 血管生物学
- 公衆衛生
背景:
- 診療室内における静止血圧 (BP) の不調は心血管リスクの予測因子として知られています.
- 家庭で測定された静止血圧反応の流行と動脈硬化関連は,大規模な集団では十分に確立されていません.
研究 の 目的:
- 家庭内静止性低血圧 (家庭内静止性OH) と家庭内静止性高血圧 (家庭内静止性OHT) の流行を調査する.
- 頸動脈斑,脈波速度 (PWV),冠動脈カルシウムスコア (CACS) を含む動脈硬化症のマーカーと家庭でのOHと家庭でのOHTの関連を調べる.
主な方法:
- スウェーデンのCArdioPulmonary bioImage Study (SCAPIS) に参加した4556人の横断分析.
- 家庭での血圧測定には,オムロン M10-IT 装置を用いた2つの静止血圧測定が含まれていました.
- ホメオパシーとは,静脈血圧の低下 ≥20mmHg または静脈血圧の低下 ≥10mmHg と定義される. OHTは静脈動脈圧が 20mmHg以上上昇すると定義される.
主要な成果:
- 参加者の6. 4%がホームOH (n=293) で,3. 1%がホームOHT (n=139) でした.
- 家庭でのOHまたは家庭でのOHTの被験者は,正常な反応の被験者と比較して,頸動脈プラークの有病率が高かった (65. 5%,64. 7%,55. 3%).
- ホームOHは,より高いPWV (9. 2±1. 4対8. 9±1. 3m/ s) と,CACS≥100 (17. 4%対11. 6%) の可能性の増加と関連していました. 家庭用OHTとPWVまたはCACSとの有意な関連性は見つかりませんでした.
結論:
- 自宅で測定された正静性低血圧と高血圧は,亜臨床性動脈硬化症と関連しています.
- 家庭での静止性低血圧は特に動脈の硬化に関連しており,単純な血圧低下以上の臨床的関連性を示唆しています.
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