エピネフリンを含むリドカインと画像誘導コア・ニードル乳房検診後の血腫リスク
Eric E Davis1, Sueann Mark1, Genevieve A Woodard2
1Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA.
Journal of breast imaging
|August 30, 2025
まとめ
エピネフリンを含むリドカインは,9ゲージのコア・ニードル乳房生検 (CNBBs) で血腫のリスクを有意に低下させた. この発見は,特定の生体検査の際に患者の安全性を向上させる可能性があることを示唆しています.
科学分野:
- 放射線科
- 介入放射線学
- 腫瘍学
背景:
- コア・ニードル・ブレストバイオプシー (CNBB) は一般的な手順です.
- 血腫の形成はCNBBの潜在的な合併症です.
- CNBBs後の血腫のリスクを減らすためのリドカインにおけるエピネフリンの役割は十分に確立されていません.
研究 の 目的:
- エピネフリンを含むリドカインとリドカインのみを使用した後の症状性血腫のリスクを比較する.
- 画像誘導 CNBB で血腫のリスクを低減するエピネフリンの有効性を評価する.
主な方法:
- 12ヶ月間にわたって実施されたCNBBの遡及的レビュー.
- 患者はリドカイン単独投与か,エピネフリンを含むリドカイン投与を受けた.
- 生検後の合併症は,症状のある血腫を含む,ナビゲーター看護師によって評価されました.
- マンモグラフィは血腫を検査し ロジスティック回帰でデータを分析した.
主要な成果:
- 合計1157件のCNBBが分析された.
- 血腫リスクの有意な差異は,アメリカ指針による12〜14のCNBBでは見つかりませんでした.
- エピネフリンを含むリドカインは,9- gauge CNBBsの後,症状の有意な減少 (0. 6% 対 4. 1%) と,マンモグラフィ的に明らかな血腫 (16. 1% 対 41. 2%) を示した.
結論:
- エピネフリンを含むリドカインは,9-gauge CNBBの後,血腫の発生率を低減するのに有効です.
- エピネフリンを含むリドカインは,血腫のリスクを低下させ,患者の安全性を高める可能性があります.
関連する概念動画
Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia
557
Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...
One of the advantages of...
557
Cardiac Catheterization IV: Nursing Management
193
Nursing responsibilities before cardiac catheterization include:Assess for allergies and establish baseline health status.Before cardiac catheterization, assess the patient for allergies to contrast dye. Perform a comprehensive baseline assessment, including vital signs, heart and breath sounds, and a neurovascular assessment of the extremities, noting distal pulses, skin color, and temperature. Instruct the patient to fast for 8-12 hours before the procedure. Evaluate baseline laboratory...
193
Local Anesthetics: Clinical Application as Epidural Anesthesia
498
Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
498
Local Anesthetics: Adverse Effects
491
While local anesthetics are generally safe and well-tolerated, they can occasionally cause adverse effects that vary in severity. Local anesthetics can induce toxicity at two distinct levels. They can either produce local effects through direct contact with the neural elements or be absorbed into the bloodstream from the injection site, leading to systemic effects.
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
491
Endoscopic Studies II: Thoracocentesis
495
Thoracentesis(Thoracocentesis), commonly known as pleural tap, is a medical procedure where a 22 gauge needle is inserted into the pleural space, the area between the lung and chest wall. This procedure is commonly performed to diagnose or treat various respiratory disorders.
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
495
Local Anesthetics: Common Agents and Their Applications
545
Local anesthetics (LAs) are commonly used for various applications in medical and dental procedures. Some of the common agents used are cocaine, lidocaine, and bupivacaine.
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...
545


