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Updated: Sep 9, 2025

Induction of Alloantigen-specific Anergy in Human Peripheral Blood Mononuclear Cells by Alloantigen Stimulation with Co-stimulatory Signal Blockade
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前回のペムブロリズマブとベンダムスティン療法によるアルジェニック幹細胞移植は,ニボルマブ後に再発した再発性古典ホジキンリンパ腫で完全な代謝反応を誘発する

Ugo Giordano1, Agnieszka Kuś2, Karolina Kędziora2

  • 1Department and Clinic of Endocrinology and Internal Medicine, Wroclaw Clinical Hospital, Ludwika Pasteura 4 Street, Wroclaw, 50-367, Poland. ugogiordano1@gmail.com.

Annals of hematology
|August 30, 2025
PubMed
まとめ

このケース・スタディは,アロゲン性造血幹細胞移植 (allo-HCT) が再発性/耐性古典ホジキンリンパ腫 (r/rcHL) の治療可能であることを示しています. 移植前のチェックポイント阻害剤 (CPI) 療法は,移植対リンパ腫効果を高めることで,治療結果を改善する可能性があります.

キーワード:
アロゲン性幹細胞移植古典的なホジキンリンパ腫ニボルマブペムブロリズマブ耐火性

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