小児のAcinetobacter lwoffiiバクテレミアの臨床的特徴,抗菌剤の感受性,治療の特徴および結果:症例シリーズ
Ömer Güneş1,2, Aslınur Özkaya-Parlakay3, Ahmet Yasin Güney3
1Department of Paediatric Infectious Diseases, Ankara City Hospital, Ankara, Turkey. dromergunes@gmail.com.
まとめ
小児におけるAcinetobacter lwoffiiバクテレミアは治療可能である. 有効な治療には,アミカシン,セフタジジム,コリスチンなどの広範囲の抗生物質が含まれ,好ましい結果をもたらします.
科学分野:
- 子供 の 感染症
- 臨床微生物学
- 病院 で 感染 する 病気
背景:
- Acinetobacter lwoffiiは病院で感染する 機会性病原体です
- 小児患者のA. lwoffiiによるバクテレミアには,臨床パターンと効果的な治療戦略の理解が必要です.
研究 の 目的:
- 臨床的特徴,抗生物質感受性,治療方法,A. lwoffiiバクテレミアの小児患者のアウトカムを分析する.
- 子供におけるA. lwoffiiバクテレミアの最適な治療戦略を特定する.
主な方法:
- 2019年9月から2022年12月までのA. lwoffiiバクテレミアの小児患者の遡及症例シリーズ.
- 人口統計データ,基礎疾患,感染源,抗菌剤の感受性,治療計画,臨床結果の分析
主要な成果:
- 12人の小児患者が含まれており,91. 7%がアミカシンに対して, 83. 3%がセフタジジームおよびコリスチンに対して感受性があった.
- すべての患者は,広範囲のベータ・ラクタムを含む,感受性指向の単独療法または併用療法で好ましい結果を達成しました.
- 持続的な細菌血症,再発,または感染関連の死亡率は観察されなかった.
結論:
- Acinetobacter lwoffiiは,入院児における病院内感染性細菌血症の重要な原因である.
- 単体またはアミカシンまたはコリスチンと併用した広範囲のベータラクトム抗生物質による治療は有効です.
- 小児患者のA. lwoffiiバクテレミアの成功管理には,病原体指向療法が不可欠です.
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