タンパク質リン酸塩2Aは,ATGタンパク質リン酸化誘導によるCandida albicansバイオフィルムの薬剤耐性を影響する

Jiadi Shen1, Chenyu Weng1, Shuxian Zhu1

  • 1Department of Endodontics, The Affiliated Stomatological Hospital of Nanjing Medical University, Nanjing, China; State Key Laboratory Cultivation Base of Research, Prevention and Treatment for Oral Diseases, Nanjing, China.

PubMed
まとめ

タンパク質フォスファタゼ2A (PP2A) は,カンジダ・アルビカン (C. albicans) のバイオフィルム形成と薬剤耐性をオートファギーの誘導によって調節する. PP2Aを阻害することで,C. albicansの感染に対する治療策を提供することができる.

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