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Updated: Sep 9, 2025

Author Spotlight: Advancements in Understanding and Combatting Shigella Infections
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Author Spotlight: Advancements in Understanding and Combatting Shigella Infections

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マクロファージは,TLR誘発のIL-12とIFN-γ経由で,腸内上皮細胞ニッチからシゲラの排出をオーケストラ化します

Kevin D Eislmayr1, Charlotte A Nichols1, Fitty L Liu1

  • 1Division of Immunology & Molecular Medicine, Department of Molecular & Cell Biology, University of California, Berkeley, Berkeley, CA, USA.

Cell host & microbe
|August 30, 2025
PubMed
まとめ

中性粒子はシゲラ菌を 制御する鍵ではありません しかしマクロファージは 重要な免疫シグナル分子を生成することで 宿主防御に不可欠です

キーワード:
IFN-g についてIL-12 についてシゲラシゲロシス生まれつきの免疫腸内皮質細胞マクロファージマウスモデル中性粒子

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