関連する実験動画

Updated: Sep 9, 2025

Purification of the Membrane Compartment for Endoplasmic Reticulum-associated Degradation of Exogenous Antigens in Cross-presentation
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Purification of the Membrane Compartment for Endoplasmic Reticulum-associated Degradation of Exogenous Antigens in Cross-presentation

Published on: August 21, 2017

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核酸に依存する形状の変化 輸送機による直接ペプチドの輸出

James Lee1, Victor Manon2, Jue Chen3

  • 1Laboratory of Membrane Biophysics and Biology, the Rockefeller University, New York, NY 10065, USA.

Immunity
|August 30, 2025
PubMed
まとめ

抗原処理に関連するトランスポーター (TAP) は,免疫反応のためにペプチドをエンドプラズマの網膜に移動させます. TAPがペプチドを輸送し放出し ERのストレスを防ぐ方法を明らかにします

キーワード:
ABCトランスポーターMHC-I適応免疫抗原の表示ヌクレオチド結合領域抗原処理に関連するトランスポーター

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Targeting proteins to the ER
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Sec61 protein conducting channel
In eukaryotes, the translocon complex comprises a core heterotrimeric translocator channel called the Sec61 complex. This channel includes three transmembrane proteins, Sec61α, Sec61β, and Sec61γ, and is the largest subunit of the...
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