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Updated: Sep 9, 2025

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様々な免疫抑制性疾患を有するCOVID-19患者のレムデシビル耐性変異の特徴

Takaya Ichikawa1, Tomokazu Tamura2, Naganori Nao3

  • 1Department of Hematology, Faculty of Medicine, Hokkaido University, Sapporo, Japan; Department of Microbiology and Immunology, Faculty of Medicine, Hokkaido University, Sapporo, Japan.

Antiviral research
|August 30, 2025
PubMed
まとめ

免疫力が低下した患者では,SARS-CoV-2 nsp12 遺伝子の変異によりレムデシビル耐性が生じることがあります. これらの変異は,特に重度の免疫不全の個体では,ウイルスの成長と薬の有効性に影響します.

キーワード:
抗ウイルス耐性コロナウイルス免疫抑制レムデシビルSARS-CoV-2についてnsp12 について

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