乳牛のStreptococcus uberis感染時の臨床結果に対するSaccharomyces cerevisiae発酵剤による栄養補給の効果
Q K Kolar1, K C Krogstad1, T H Swartz1
1Department of Animal Science, Michigan State University, East Lansing, MI.
Journal of dairy science
|August 30, 2025
まとめ
Saccharomyces cerevisiae発酵剤 (SCFP) の補給は,Streptococcus uberis mastitisに罹患した乳牛の臨床結果や乳産量を改善しなかった. 自然に発生する乳房炎についてはさらなる研究が必要である.
科学分野:
- 獣医学
- 動物科学
- 微生物学
背景:
- Streptococcus uberisは乳牛の乳炎の重要な原因であり,効果的なワクチンが不足しているため,しばしば抗生物質の治療が必要になります.
- Saccharomyces cerevisiae発酵産物 (SCFP) は乳牛の体細胞数 (SCC) の減少と関連している.
研究 の 目的:
- 実験的にStreptococcus uberisに感染した乳牛の臨床および生産パラメータに対する経口SCFP補給の影響を調査する.
- S. uberisによる乳内感染の影響を軽減するSCFPの有効性を評価する.
主な方法:
- 42頭の健康な乳母牛を対象にランダム化臨床試験が行われました.
- 治療群は毎日SCFPまたは90日間対照ダイエット (粉砕されたトウモロコシ) を受けた.
- 牛乳のサンプルをSCC,バクテリアコロニー,および乳房炎の臨床的徴候のために分析し,生産データ (DMI,牛乳収量,成分) も記録した.
主要な成果:
- SCFPのサプリメントは,試験のどの段階においても,乾物摂取量 (DMI),ミルク生産量,またはミルク成分を有意に変化させなかった.
- SCFP治療群と対照群の乳中のS. uberisコロニー数やSCCの有意な違いは観察されなかった.
- SCFPを投与した牛は統計的に有意ではないが,臨床乳房炎の発症が遅れた傾向を示し,対照群と比較して細菌学的治癒までの期間がわずかに短かった.
結論:
- SCFPの経口補給は,この研究の条件下で,Streptococcus uberisに挑戦された乳牛の臨床または生産結果の改善に効果を示さなかった.
- 牛の白血病ウイルスに感染した牛のサブセットで,DMIと乳産量に対する潜在的な肯定的な効果が観察され,さらなる調査が必要であった.
- 将来の研究は,自然に発生する乳房炎の症例に焦点を当て,SCFPの異なる用量または配方を探求すべきである.
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