Metrnl/IL-41によるマクロファージの細胞外トラップの抑制は,喘息における呼吸道の再構築を抑制する

Kangni Feng1, Jiemei Cen1, Chunyan He1

  • 1Department of Pulmonary and Critical Care Medicine, The Third Affiliated Hospital of Sun Yat-sen University, Institute of Respiratory Disease of Sun Yat-sen University, Guangzhou, China.

Biochemical pharmacology
|August 30, 2025
PubMed
まとめ

マクロファージの細胞外トラップ (MET) は 喘息の炎症と呼吸道の再構築を促します Metrnl/ IL-41は保護性サイトカインで,METsによって引き起こされる上皮の変化を抑制し,マウスの喘息症状を軽減します.

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