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Updated: Sep 9, 2025

In Vitro Analysis of PDZ-dependent CFTR Macromolecular Signaling Complexes
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CLIC5Aは,エズリンの開いた形状と活性形状に結合し,安定させます

Md Mizanur Rahman1, Jong S Kim1, Laiji Li1

  • 1Department of Medicine.

The Journal of biological chemistry
|August 30, 2025
PubMed
まとめ

クロライドチャネルイメージフィルター5A (CLIC5A) はエズリンに直接結合し,その活性構造を安定させ,小さなGTPーAの活性化を促します. この相互作用は,毛細胞とポドサイトの細胞構造とシグナル伝達を維持するために不可欠です.

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