関連する実験動画

Updated: Sep 9, 2025

Functional Assessment of Kinesin-7 CENP-E in Spermatocytes Using In Vivo Inhibition, Immunofluorescence and Flow Cytometry
09:41

Functional Assessment of Kinesin-7 CENP-E in Spermatocytes Using In Vivo Inhibition, Immunofluorescence and Flow Cytometry

Published on: December 28, 2021

1.9K

CENP-Fのファルネシレーション依存性キネトコーアターゲティングは卵細胞のメオティック進行と女性の生育能力に不可欠である

Ou Zhong1, Congjing Wang2, Junqiang Zhang2

  • 1State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China; Center of Reproduction and Genetics, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, China.

American journal of obstetrics and gynecology
|August 30, 2025
PubMed
まとめ

この研究は,CENP-Fのファルネシレーションが哺乳類の卵細胞微分化と染色体分離に不可欠であることを明らかにしています. CENP-Fの遺伝的欠陥は女性の不妊症と卵細胞成熟停止に関連しており,潜在的な診断マーカーとして特定されています.

キーワード:
CENP-F についてファーネシレーション女性不妊症キネトコア卵細胞メタフェーズI停止スピンドル・アセンブリ・チェックポイント

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