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喉頭逆流症に対する食事の推奨の有効性:臨床実務と研究のための体系的レビュー

Jérôme R Lechien¹

¹Department of Surgery, Faculty of Medicine, UMONS Research Institute for Health Sciences and Technology, University of Mons (UMons), Mons, Belgium; Department of Otolaryngology - Head & Neck Surgery, Foch Hospital, School of Medicine, UFR Simone Veil, Université Versailles Saint-Quentin-en-Yvelines (Paris Saclay University), Paris, France; Department of Otolaryngology, Polyclinic of Poitiers, Elsan Hospital, Poitiers, France; Department of Otolaryngology-Head & Neck Surgery, CHU Saint-Pierre (CHU de Bruxelles), Brussels, Belgium.

Journal of voice : official journal of the Voice Foundation

|August 30, 2025

まとめ

低脂肪,アルカリ性,高タンパク質の食品のような食事の変化は,単独または薬剤で,喉頭逆流症 (LPRD) の症状を効果的に管理することができます. ダイエットと薬の効果を比較するにはさらなる研究が必要です.

科学分野:

胃腸内科
耳鼻喉科
ダイエット科学

背景:

胃酸が喉を刺激する状態です.
LPRDの管理にはしばしば食事の変更が推奨されますが,その有効性は徹底的な評価を必要とします.

研究の目的:

LPRDと診断された患者のための食事の推奨の有効性に関する既存の文献を体系的にレビューする.
LPRDの症状軽減に対する様々な食事介入の影響を評価する.

主な方法:

PubMed,Scopus,Cochrane Libraryのデータベースを介して包括的な文献検索が行われました.
PRISMAとMINORSの基準を用いて,868人の患者を対象とした10件の試験を分析した.
試験設計には,前向きな制御,前向きな無制御,および後向きなシリーズが含まれていた.

主要な成果:

特に低脂肪,無アルコール,低カフェイン,およびアルカリ性ダイエットの遵守は,未治療のLPRD患者の症状の有意な減少につながりました (54% - 83. 3%).
特定のダイエット (アルカリ性,低脂肪,高タンパク質,グルテンフリー) は,陽子ポンプ阻害剤療法にもかかわらず,耐性症候群の患者に緩和をもたらしました.
食事と薬の組み合わせによる治療は,薬のみと比較して優れた結果をもたらしたが,研究品質は一般的に低い.

結論:

低脂肪,高タンパク質,低糖,およびアルカリ性ダイエットを含む食事介入は,LPRDの単独または補助的な治療として有望である.
LPRDの標準的な医療療法に対する食事介入を直接比較するために,高品質のランダム化制御試験が必要である.
将来の研究では,LPRD患者の食事管理の長期的な効果も調査する必要があります.

キーワード:

ダイエット頭の首の手術喉科耳鼻喉科逆流音声について

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