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Updated: Sep 9, 2025

Author Spotlight: Advancements in Molecular Biomarker Testing for Non-Squamous Non-Small Cell Lung Cancer
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先進性非小細胞肺がん患者におけるEGFR単一治療の実用的な結果に対する BRCA1/ 2およびPALB2の偶発的な変異の影響

Chetan V Vakkalagadda1, Leslie Bucheit2, Keelia Clemens2

  • 1Department of Medicine, Division of Hematology/Oncology, School of Medicine, Oregon Health and Science University, Portland, OR; Department of Medicine, Division of Hematology/Oncology, Northwestern University, Chicago, IL.

Clinical lung cancer
|August 30, 2025
PubMed
まとめ

EGFR単独治療で治療されたBRCA1/ 2またはPALB2の生殖系変異体 (gBRCA/ PALB2+) とEGFR変異の進行性非小細胞肺がん (aNSCLC) の患者は,治療期間が数値的に短く,全体生存期間は対照群と比較して長かった.

キーワード:
ビッグデータ肺がんにおける腫瘍性要因精密医療現実世界の証拠 (RWE)ctDNA について

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