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Updated: Sep 9, 2025

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
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Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics

Published on: March 15, 2024

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TP53によるPHKG2の転写活性化は,頭頸部状細胞がんにおけるNRF2の核輸出を通じてフェロプトーシスを促進する

Yalian Yu1, Meng Luan2, Jian Zang1

  • 1Department of Otorhinolaryngology, The First Affiliated Hospital of China Medical University, Shenyang, PR China.

Cell death & disease
|August 30, 2025
PubMed
まとめ

この研究は,TP53がPHKG2を活性化し,頭頸がんにおけるフェロプトーシスを促進する新しい経路を明らかにした. この発見は 癌治療の成果を向上させる 新しい治療目標の可能性を秘めています

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Yeast As a Chassis for Developing Functional Assays to Study Human P53

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