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Updated: Sep 9, 2025

Desthiobiotin-Streptavidin-Affinity Mediated Purification of RNA-Interacting Proteins in Mesothelioma Cells
11:11

Desthiobiotin-Streptavidin-Affinity Mediated Purification of RNA-Interacting Proteins in Mesothelioma Cells

Published on: April 25, 2018

8.3K

長い非コーディングRNAH19は,HDAC1媒介のWT1/Sp1スイッチを通して,メソチアル原細胞におけるメソキマのような侵入性フェノタイプの獲得を促進する

Giulio Bontempi1,2, Federica Michetti1,2, Michela Terri1,2

  • 1Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy.

Cell death & disease
|August 30, 2025
PubMed
まとめ

長い非コーディングRNA H19は,メソセリアルからメゼンキマへの移行を誘導することによって,腹膜繊維症を促進する. HDAC1を阻害すると,H19プロモーターへの転写因子の結合が変化し,治療対象となる.

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