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Updated: Sep 9, 2025

Pre-Conditioning the Airways of Mice with Bleomycin Increases the Efficiency of Orthotopic Lung Cancer Cell Engraftment
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腫瘍コラーゲン繊維の調整は,吸入RNAによる肺がん免疫療法を強化する

Bin Hu1,2, William Stewart3, Qijing Chen1,2

  • 1Shanghai Frontiers Science Center of Drug Target Identification and Delivery, School of Pharmaceutical Sciences, Shanghai Jiao Tong University, Shanghai, China.

Nature communications
|August 30, 2025
PubMed
まとめ

この研究では,脂質ナノ粒子 (LNP) を使用した吸入療法が肺がんに直接投与されます. この新しいアプローチは,腫瘍の微小環境 (TME) を改変し,T細胞の活動を改善することにより,免疫療法の有効性を高めます.

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