乳がん患者の長期的な心理的結果と生活の質に対するがん治療の影響

Yuan Yang¹, Yanjie Zhao^2,3, Kaimin Yao¹

¹Guangdong Mental Health Center, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, 510080, Guangdong, China.

BMC cancer

|August 30, 2025

まとめ

乳がん患者は,治療後48ヶ月間,うつ病,不安,がん再発の恐れ,および痛みが減った. 乳房切除手術を受けた患者は,より高い不安を報告しましたが,生活の質は早期に改善され,安定していました.

科学分野:

腫瘍学
心理学
健康成果研究

背景:

乳がんの生存者の長期的な身体的・心理的な健康状態の評価は極めて重要です
様々ながん治療が患者の治療結果に与える影響を理解することは生存者のケアに不可欠です

研究の目的:

治療後48ヶ月間におけるうつ,不安,がん再発の恐れ (FCR),痛み,生活の質 (QOL) の変化を調査する.
異なる治療方法 (手術,化学療法,放射線療法) が,乳がん患者の長期的な結果とQOLにどのように影響するかを調べる.

主な方法:

縦断的な見通し研究設計
検証されたアンケート (PHQ- 9, GAD- 7, FCR- 7, MPQ- VAS,WHOQOL- BREF) を利用し,初期,12,24および48ヶ月で投与した.
長期的結果のための混合モデル繰り返し測定 (MMRM) 分析

主要な成果:

うつ病 (PHQ-9),不安症 (GAD-7),FCR,および痛みのスコアは,基値から48ヶ月まで有意に減少しました.
生活の質 (QOL) のスコアは12ヶ月改善され,その後は安定しました.
乳房切除手術を受けた患者は,48ヶ月後の部分性乳房切除手術を受けた患者と比較して,より高い不安レベルを報告した.

結論:

乳がん患者は,治療後48ヶ月以内に,心理的苦痛と痛みの有意な改善と,改善されたQOLを示しています.
治療方法,特に乳房切除は生存者の持続的な高い不安レベルと関連しています.
発見は,乳がん患者に対する継続的な心理的支援と,適応した生存ケアプランの必要性を支持しています.

キーワード:

不安について乳がんうつ病癌が再発する恐れ生活の質

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