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Updated: Sep 9, 2025

Using Mouse Oocytes to Assess Human Gene Function During Meiosis I
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JARID2のホモジゴス変異は,ブラストレーションの効率が損なわれる女性不妊を引き起こす

Jiaqi Sun1, Huiling Hu2,3, Fei Meng2

  • 1Center for Medical Genetics, School of Life Sciences, Central South University, Changsha, 410013, China.

Journal of ovarian research
|August 30, 2025
PubMed
まとめ

JARID2遺伝子の新型変異は,これまで解明されていない助産技術 (ART) の失敗の原因である,破裂効率 (CBE) を引き起こす. この発見は不妊症の遺伝子診断を拡大し 初期胚の発達に関する新しい洞察をもたらします

キーワード:
JARID2 変種初期の胚の発達女性不妊症ヒストンのメチル化

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