関連する実験動画

Updated: Sep 9, 2025

An In vitro Co-infection Model to Study Plasmodium falciparum-HIV-1 Interactions in Human Primary Monocyte-derived Immune Cells
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An In vitro Co-infection Model to Study Plasmodium falciparum-HIV-1 Interactions in Human Primary Monocyte-derived Immune Cells

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HIVとマラリアの単発および共感染におけるドゥレテグラビールとアルテメテル・ルメファントリンの薬物相互作用:ガーナの薬剤遺伝分析

Nicholas Ekow Thomford1,2,3,4, Tracy Kellermann5, Joel Adu Twum6

  • 1Pharmacogenomics and Genomic Medicine Group, School of Medical Sciences, College of Health and Allied Sciences, University of Cape Coast, Cape Coast, Ghana. nthomford@ucc.edu.gh.

AIDS research and therapy
|August 30, 2025
PubMed
まとめ

ガーナでHIVとマラリアの共感染のためにアルテメテル・ルメファントリンとドゥルテグラビル (DTG) を併用した結果,薬剤濃度が低下した. これは治療の効果と結果に影響し,薬剤遺伝学的考慮の必要性を強調します.

キーワード:
CYP3A4CYP3A5UGT1A1 についてアルテメテル ルメファントリンDTG についてドルテグラビールHIV ウイルスファルマゲノミクスプラズマ薬物濃度ウイルス負荷

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