関連する実験動画

Updated: Sep 9, 2025

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
07:41

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators

Published on: February 20, 2018

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新たに設計されたアゴニストによるG-CSFR信号の調節

Timo Ullrich1, Christoph Pollmann2, Malte Ritter3

  • 1Max Planck Institute for Biology, Department Protein Evolution, 72076 Tübingen, Germany; Friedrich Miescher Laboratory of the Max Planck Society, 72076 Tübingen, Germany.

Molecular therapy : the journal of the American Society of Gene Therapy
|August 31, 2025
PubMed
まとめ

粒細胞コロニー刺激因子受容体 (G-CSFR) の設計されたアゴニストは,増殖よりも血液形成幹細胞の分化を促進します. これらの新種のサイトカインは,標的薬の発見のための安定性と治療の可能性を高めています.

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