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Updated: Sep 9, 2025

Examining the Conformational Dynamics of Membrane Proteins in situ with Site-directed Fluorescence Labeling
11:55

Examining the Conformational Dynamics of Membrane Proteins in situ with Site-directed Fluorescence Labeling

Published on: May 29, 2011

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AlphaFold2は,電圧ゲートチャネルスーパーファミリーの構成変遷を捕捉する

Elaine Tao1, Ben Corry1

  • 1Division of Biomedical Science and Biochemistry, Research School of Biology, Australian National University, Canberra, ACT 2601, Australia.

Biophysical journal
|August 31, 2025
PubMed
まとめ

カチオンチャネルにおける電圧感知ドメインの計算モデルでは,様々な構成状態が示される. AlphaFold2は,チャネル機能に関する研究を支援し,中間とエンドポイントの構造を予測する見込みを示しています.

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Voltage-gated ion channels are transmembrane proteins that open and close in response to changes in the membrane potential. They are present on the membranes of all electrically excitable cells such as neurons, heart, and muscle cells.
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