日本 で の 犬 の ヘルペス ウイルス-1 の 目 感染症: 症例 報告
Kensuke Usami1, Hiroyuki Komatsu1, Minori Akasaka1
1Animal Eye Care-Tokyo Animal Eye Clinic, Tokyo, Japan.
Veterinary ophthalmology
|August 31, 2025
まとめ
犬のヘルペスウイルス1 (CHV-1) は,角膜の潰瘍,涙の発生の減少,角膜の感受性の低下を伴う成人犬の眼感染症を引き起こす可能性があります. 抗ウイルス治療は病変の解消と眼機能の改善につながった.
科学分野:
- 獣医眼科
- 犬の感染症
- 眼ウイルス学
背景:
- 犬のヘルペスウイルス1 (CHV-1) は,犬における一般的なウイルス病原体で,通常は子犬に感染します.
- 成犬の眼の症状はあまり報告されていない.
研究 の 目的:
- 成犬におけるCHV-1による眼感染症の臨床症状と治療結果を記録する.
- CHV-1 眼疾患に関連する潜在的な非典型的臨床特徴を強調する.
主な方法:
- 5歳のフレンチ・ブルドッグの症例研究が実施された.
- 結膜スランプのポリメラーゼ連鎖反応 (PCR) 分析により診断が確認された.
- 治療は局所用イドクシウリジンで,PCRと眼科検査によるモニタリングが行われました.
主要な成果:
- 犬は角膜潰瘍,涙の生成の減少,角膜低聴症を発症した.
- 抗ウイルス治療は角膜の潰瘍の解消と角膜の敏感性と涙の生成の改善をもたらしました.
- 定量PCRにより,治療後のウイルス発散の減少が確認されました.
結論:
- 日本で初めて成人犬にCHV-1の眼感染症が報告されました.
- CHV-1は典型的な角膜潰瘍だけでなく,それに関連した角膜低聴症と定量的な涙欠乏症を引き起こす可能性があります.
- 早期診断と抗ウイルス治療は,CHV-1の眼感染症の管理に不可欠です.
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