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Updated: Sep 9, 2025

Ferric Chloride-induced Murine Thrombosis Models
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冠動脈疾患における網状血小板:多次元的なアプローチにより,前血栓シグナル伝達と新たな治療目標が明らかになる

Kilian Kirmes1,2, Jiaying Han1,2, Melissa Klug1,2,3

  • 1Department of Internal Medicine I, University hospital rechts der Isar, Technical University of Munich, Munich, Germany.

European heart journal
|August 31, 2025
PubMed
まとめ

冠動脈疾患 (CAD) の網状血小板 (RP) は,異なる分子経路のために過反応性である. GPVIとPI3K経路を標的とした治療は,高血圧のCAD患者の抗血小板治療において有望な戦略である.

キーワード:
GPVI について冠動脈疾患マスサイトメトリー網状血小板血栓細胞トランスクリプトミクス

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