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Updated: May 11, 2026

A Neuronal and Astrocyte Co-Culture Assay for High Content Analysis of Neurotoxicity
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FPR2/ALX経路の分子成分は,マネブ誘発の毒性をもたらすために,アストロサイト-ニューロン解離反応に参加する

Oriana N Benzi Juncos1,2, Natalia P Alza1,2, José L Cordero3

  • 1Instituto de Investigaciones Bioquímicas de Bahía Blanca (INIBIBB) - Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Camino La Carrindanga Km7 B8000, Bahía Blanca, Argentina.

Cellular and molecular life sciences : CMLS
|August 31, 2025
PubMed
まとめ

マネブ (MB) のような環境中毒物質は,炎症/解消経路を阻害することで神経変性を引き起こす. アストロサイトは,ホルミルペプチド受容体2 (FPR2/ALX) 経路に作用する脂質媒介体によってニューロンを保護する.

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