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Updated: Sep 9, 2025

Transplantation of Induced Pluripotent Stem Cell-derived Mesoangioblast-like Myogenic Progenitors in Mouse Models of Muscle Regeneration
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Published on: January 20, 2014

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RPS27Lは,液体-液体相分離を通じてIGF1をターゲットにすることで,骨髄形成と筋肉質を向上させます

Xiaoqin Liu1,2,3, Yilong Yao1,2, Junyu Yan1,2

  • 1Shenzhen Branch, Guangdong Laboratory of Lingnan Modern Agriculture, Key Laboratory of Livestock and Poultry Multi-omics of MARA, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, 518124, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|August 31, 2025
PubMed
まとめ

リボソームタンパク質S27型 (RPS27L) は,骨格筋の成長と再生を促進する. SIX4によって調節されるRPS27Lは,液体-液体相分離 (LLPS) とIGF1の相互作用により,筋細胞増殖を促進する.

キーワード:
IGF1 についてRPS27Lについて液体と液体の相分離筋肉量ミオファイバーのサイズ骨格筋

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