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Updated: Sep 9, 2025

An Adoptive Transfer Model of Rheumatoid Arthritis in Mice
07:37

An Adoptive Transfer Model of Rheumatoid Arthritis in Mice

Published on: June 6, 2025

352

レプチンは,シノビオサイトに対するインタールイキン-1ベータの炎症効果を強める. 骨関節炎細胞モデルにおけるDHAとEPAの潜在的な予防的役割

Atitaya Wayupat1, Prachya Kongtawelert1, Peraphan Pothacharoen1

  • 1Thailand Excellence Center for Tissue Engineering and Stem Cell, Department of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand.

Biochemistry. Biokhimiia
|August 31, 2025
PubMed
まとめ

肥満に関連した関節炎 (OA) は,関節の炎症を伴う. レプチンは,特定の経路 (p65,STAT3) を活性化することによって,この炎症を促進します. オメガ3脂肪酸 (DHA,EPA) は,このレプチン誘発性シノビティスを抑制することができます.

キーワード:
IL-1βレプチン肥満オメガ3脂肪酸骨関節炎シノビオサイト

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