COVID-19 パンデミック前,その間,その後の日本における抗咳剤の使用の全国的な傾向:国家データベースを用いた記述的研究
Tomohiro Akaba1, Musashi Ueda1, Yutaro Horie1
1Department of Respiratory Medicine, Tokyo Women's Medical University School of Medicine, 8-1 Kawada-cho, Shinjuku-ku, 162-8666, Tokyo, Japan.
Respiratory investigation
|August 31, 2025
まとめ
日本では,COVID-19の流行の間,慢性疾患ではなく急性呼吸器疾患の処方薬が減少した. これは証拠に基づいた処方法の必要性を強調しています
科学分野:
- 薬理学について
- 公衆衛生
- 医療サービス研究
背景:
- 抗咳剤は日本では頻繁に処方され,しばしば確立された臨床ガイドラインから逸脱する.
- COVID-19 パンデミックを含む外部要因が,抗咳処方パターンに及ぼす影響については,さらなる調査が必要である.
研究 の 目的:
- 2018年から2022年までの日本における抗咳剤 (中央作用薬とカンポ薬) の処方量と費用の動向を分析する.
- 同じ期間の慢性疾患の治療薬の傾向と比較する.
- COVID-19 パンデミックの抗咳処方行動に対する潜在的な影響を評価する.
主な方法:
- 2018年から2022年までの国立データベース (NDB) のオープンデータを活用した記述的研究.
- 抗咳薬や慢性疾患薬の薬剤のカテゴリ,量,費用を含む年次処方薬のデータ分析
- 抗咳薬と慢性疾患薬の処方傾向の比較分析
主要な成果:
- 中央作用抗咳薬とカンポ薬の両方の処方箋は,2018年から2019年にかけて安定し,2020年から2021年にかけて減少し,2022年には部分的に回復した.
- 抗咳薬の処方費のコストは,観測された量の傾向を反映した.
- パンデミック期間中に慢性疾患を治療する薬剤の処方パターンの有意な変化は認められなかった.
結論:
- パンデミック中に抗咳処方薬の減少は,医療利用の減少と急性呼吸器感染症の減少を反映している可能性が高い.
- 抗咳剤は慢性疾患ではなく 主に急性疾患に使用されていることが 示唆されています
- 日本では,抗咳剤のより適切な,証拠に基づいた処方法を推進する明確な必要性があります.
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