腎臓インタースティシャル線維症における免疫関連ハブ遺伝子の統合的生物情報学的発見およびin vivo検証

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Tefei Lu1, Sheng Chen1, Lei Zhang1

  • 1Department of Urology, Ningbo Medical Central Lihuili Hospital, Ningbo, Zhejiang 315040, China.

Computational biology and chemistry
|August 31, 2025
PubMed
まとめ

この研究では,腎臓間繊維症 (RIF) の進行に関与する5つの重要な遺伝子 (GPR18,CCL5,CCR5,CCL19,CXCL9) が特定されました. これらの遺伝子は免疫細胞の調節と関連しており,RIF治療の潜在的治療標的を代表しています.

キーワード:
バイオ情報学DEG について免疫の浸透腎臓間繊維症

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