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Updated: Sep 9, 2025

Spectrophotometric Screening for Potential Inhibitors of Cytosolic Glutathione S-Transferases
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Spectrophotometric Screening for Potential Inhibitors of Cytosolic Glutathione S-Transferases

Published on: October 10, 2020

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炎症およびがん治療における応用を持つ強力なグルタチオントランスファーゼOmega-1阻害剤の開発

Yiyue Xie1, Yuji Nakano1, Padmaja Tummala2

  • 1Australian Translational Medicinal Chemistry Facility, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, 3052, Australia.

European journal of medicinal chemistry
|August 31, 2025
PubMed
まとめ

炎症性疾患とがんの治療に有望である. 化合物10uは強力なGSTO1- 1阻害体となり,炎症を軽減し,化学療法の有効性を高める.

キーワード:
抗がん剤抗炎症剤コヴァレント阻害剤GSTO1- 1 阻害剤グルタチオントランスファーゼOmega-1NLRP3炎症ゾームSAR について

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