新生児重症病棟における抗菌薬の使用プロファイル: スコーピングレビュー
Francisco Clébison Chaves Lopes1, Tayssa Figueiredo Moura2, Lucas Amaral-Machado3
1Postgraduate Program in Collective Health, Faculty of Health Sciences of Trairi, Federal University of Rio Grande do Norte, Santa Cruz, Rio Grande do Norte, Brazil.
Journal of the American Pharmacists Association : JAPhA
|August 31, 2025
まとめ
このスコーピングレビューでは,新生児集中治療室 (NICU) での抗菌薬の使用が検討されています. 発見は,感染リスクに直面している脆弱な新生児に対する より安全な抗菌薬の実践を促すでしょう.
科学分野:
- 新生児医学
- 感染症
- 薬理学について
背景:
- 新生児は免疫系が不完全で 感染症に易く感染します
- 侵襲的処置や長期の入院,低出生体重などの要因は 新生児の感染リスクを悪化させる.
- 新生児集中治療室 (NICU) での抗菌薬の使用は,特徴づけが必要です.
研究 の 目的:
- NICUでの抗菌薬の使用の範囲調査を実施する.
- 新生児の集中治療施設での抗菌薬の使用パターンとプロフィールを特徴づける.
- 新生児に対する抗菌薬の処方に関する情報に基づいた意思決定のための証拠を提供すること.
主な方法:
- ジョアンナ・ブリッグス研究所 (JBI) の方法論に従ってオープンサイエンス・フレームワーク (OSF) に登録されたプロトコル.
- 複数のデータベース (PubMed,Scopus,Web of Scienceなど) の包括的な検索 そして灰色の文学
- 試験選択とデータ抽出は,PCCの枠組みに従った2人の独立した審査員によって行われました.
主要な成果:
- データの抽出は,抗菌剤の消費率,一般的な処方箋,徴候,および非表示使用に焦点を当てた.
- 含有基準は,入院した新生児の階層化可能なデータを持つNICUからの研究です.
- 抽出したデータは,図式で表で説明します.
結論:
- 研究結果は,NICUにおける抗菌剤の利用における世界的な変動を明らかにします.
- この発見は,医療従事者が抗菌剤の処方方法を最適化するのに役立ちます.
- このレビューは,新生児の抗菌薬療法のより安全で効果的な臨床実践を促進することを目的としています.
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