関連する実験動画

Updated: Sep 9, 2025

T and B Cell Receptor Immune Repertoire Analysis using Next-generation Sequencing
08:59

T and B Cell Receptor Immune Repertoire Analysis using Next-generation Sequencing

Published on: January 12, 2021

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イスラエル系ユダヤ人とパレスチナ系アラブ人におけるB細胞非ホジキンリンパ腫サブタイプに関するヨーロッパベースのポリジェニックリスクスコアと全ゲノム関連研究

Geffen Kleinstern1,2, Dennis P Robinson2, Rania Abu Seir3

  • 1Faculty of Social Welfare and Health Sciences, School of Public Health, University of Haifa, Haifa, Israel.

British journal of haematology
|August 31, 2025
PubMed
まとめ

非ホジキンリンパ腫 (NHL) のサブタイプに対する多遺伝子リスクスコア (PRS) は,イスラエル系ユダヤ人とパレスチナ系アラブ人の間で有意な関連性を示したが,ヨーロッパ系祖先と比較して効果の大きさは弱まった. 統合GWASでは,DLBCLリスクに対する新しい遺伝的位置が特定されました.

キーワード:
大型B細胞リンパ腫人種全ゲノム関連研究ノンホッジキンリンパ腫のサブタイプ多遺伝子リスクスコア

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