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青春期から成人期まで追跡されたノルウェーの若者のコホートで,タバコの使用は骨のミネラル密度レベルに影響しますか? フィット・フューチャーズ研究 (2010-2022)
Edvard H Sagelv1, Anne Winther2, Nina Emaus3
1Division of Internal Medicine, University Hospital of North Norway, Tromsø, Norway edvard.h.sagelv@uit.no.
BMJ open
|August 31, 2025
まとめ
この研究では,青少年のタバコ使用と骨のミネラル密度 (BMD) の変化との間に有意な関連性が見つかりませんでした. 適度な喫煙やスナップ使用は16歳から27歳までの骨の成長に悪影響を及ぼさなかった.
科学分野:
- 骨の健康 研究
- 青少年 の 健康
- タバコの使用の影響
背景:
- 骨のミネラル密度 (BMD) は,生涯を通じて骨格の健康に不可欠です.
- 青春期と若い成人期は 骨質の獲得にとって 重要な時期です
- この形成期間の喫煙とスナップを含むタバコの使用が BMD に与える影響は調査が必要です.
研究 の 目的:
- タバコの使用 (喫煙とスナップ) とBMDとの間の縦断的な関連を調べる.
- ノルウェーの青少年における股関節頸部,全部,全体におけるBMDの変化を評価する.
- 青春期から成人期まで 喫煙が骨の発達に 影響するかどうかを調べる
主な方法:
- ノルウェーの青少年 (年齢16~27歳) 722人を対象とした前向きな長期コホート研究.
- 二重エネルギーX線吸収測定法 (DXA) を用いて,基礎値と2つのフォローアップポイントでBMDを測定した.
- 自ら報告した喫煙とスナップの使用 (決して,時には毎日) を,BMDの変化に対して分析した.
主要な成果:
- BMDは16歳から18歳まで増加し,その後27歳までに部と部で減少した.
- 研究期間中,全身のBMDは継続的に増加した.
- 喫煙者およびスナップ使用者グループでは,統計的に有意なBMDの差は認められなかったが,18歳の女性では軽微な発見があった.
結論:
- ノルウェー人の青少年と若年成人の間では,喫煙やスナップ使用とBMDとの間に有意な縦断的な関連性が見つかりませんでした.
- 適度な喫煙は,この発達期間の骨の成長に悪影響を及ぼさないようでした.
- このコホートにおける典型的な青少年喫煙レベルは,骨の蓄積を損ねないことを示唆している.
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