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Bone Remodeling01:40

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
Bones of the Upper Limb: Humerus01:19

Bones of the Upper Limb: Humerus

The upper limb consists of the arm, forearm, wrist, and hand bones. The humerus is the single bone of the upper arm region. Proximally, it has a large, spherical, smooth head that articulates with the glenoid cavity of the scapula to form the glenohumeral or shoulder joint. The margin of the head is the anatomical neck, a residual epiphyseal plate. Laterally it extends to form bony projections called the greater tubercle and the lesser tubercle. Next to the tubercles is the surgical neck, a...
Bones of the Lower Limb: Femur and Patella01:16

Bones of the Lower Limb: Femur and Patella

The femur is the body's longest and strongest bone spanning the thigh region. Its head articulates with the acetabulum of the hip bone to form the hip joint. A minor indentation on the medial side of the femoral head, called the fovea capitis, serves as the site of attachment for the ligament of the head of the femur. This weak ligament spans the femur and acetabulum and supports the hip joint. The narrowed region below the head is the neck of the femur. The inclination angle between the neck...
Bones of the Lower Limb: Tibia and Fibula01:10

Bones of the Lower Limb: Tibia and Fibula

The tibia is the main weight-bearing bone of the lower leg. It is larger than the fibula with which it is paired. The tibia is also the second longest bone in the body and is located right below the skin. The proximal end of the tibia forms the medial and the lateral condyle, which articulates with the condyles of the femur to form the knee joint. Between the articulating surfaces is the irregular elevated area known as the intercondylar eminence that serves as the inferior attachment point for...
Bone Remodeling and Repair01:31

Bone Remodeling and Repair

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...

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Updated: May 11, 2026

Direct Mouse Trauma/Burn Model of Heterotopic Ossification
07:01

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ヘテロトップ的骨化から完全な部置換への難しい変換

Bishnu Prasad Patro1, Mainak Roy2, Abhijith K Jayan1

  • 1Orthopaedics, All India Institute of Medical Sciences Bhubaneswar, Bhubaneswar, Odisha, India.

BMJ case reports
|August 31, 2025
PubMed
まとめ
この要約は機械生成です。

ヘテロトップ的骨化 (HO) は,軟組織における異常な骨の成長である. 手術による切除と整体部置換 (THR) は,重度の部HOを効果的に治療し,患者の機能を回復させた.

キーワード:
整形外科とトラウマ外科整形外科

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科学分野:

  • 整形 術
  • 再生医療
  • 生物医学工学

背景:

  • ヘテロトップ性骨化 (HO) は,軟組織における異常な骨形成を伴うもので,神経学的損傷後にしばしば部に影響する.
  • ヒップHOの管理方法は,保守的な治療から,完全なヒップ置換 (THR) のような外科的介入まで様々です.

研究 の 目的:

  • ヒップの重度の異形骨化による手術の成功報告
  • 二重の可動性義肢で手術による切除とTHRの有効性を評価する.

主な方法:

  • ブルッカー症候群の 4 度目の左股関節の症例報告です
  • アセタブルウムと近隣の股関節からの異形骨の切除.
  • 二重の可動性プロテスを用いた整体部置換術 (THR)

主要な成果:

  • 患者さんは,広範囲の異形骨化により,股関節の動きがひどく制限されました.
  • 6ヶ月と1年の術後フォローアップでは,痛みの有意な改善が見られた.
  • 手術後の運動範囲と機能的な結果の顕著な改善が見られた.

結論:

  • 整骨外科手術と整骨外科手術は 重度の股関節関節損傷の有効な治療法です
  • 二重の可動性義肢は,HO後の複雑な部再建の管理に有利な結果をもたらします.