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Updated: Sep 9, 2025

Author Spotlight: Developing a Rat Model for Weight-Bearing Intervention to Investigate Osteonecrosis of the Femoral Head
05:55

Author Spotlight: Developing a Rat Model for Weight-Bearing Intervention to Investigate Osteonecrosis of the Femoral Head

Published on: September 27, 2024

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クロロロゲン酸は,HER2/AKT/mTORシグナル伝達経路を調節することにより,グルココルチコイド誘発の骨粗鬆症を軽減する

An-Na Xie1, Sun-Zheng-Yuan Zhang1, Yu Zhang1

  • 1Laboratory of Science and Technology Center, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China.

Journal of integrative medicine
|August 31, 2025
PubMed
まとめ

クロロロゲン酸 (CGA) は,骨の健康を改善し,骨細胞を標的として,グルココルチコイド誘発性骨粗鬆症 (GIOP) を効果的に治療します. CGAはHER2 / AKT / mTOR経路を調節し,GIOPの潜在的な治療戦略を提供します.

キーワード:
骨の形成クロロゲン酸グルココルチコイド誘発性骨粗鬆症人間の表皮成長因子受容体2オステオサイト

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