ミネラロコルチコイド受容体は,肥満と高血圧のマウスにおいて,オートファギーを誘導することによって,血管損傷を調節する

Miao Wang1, Chi Wang2, Maoxiang Zhao2

  • 1Department of Cardiology, The Sixth Medical Center of Chinese People's Liberation Army General Hospital, No.6 Fucheng Road, Beijing, 100048, China; Hypertension Center, Beijing Anzhen Hospital, No. 225 South 1st Street, Tongzhou District, Beijing 101118, China; The School of Medicine, Nankai University, No.94 Weijin Road, Nankai District, Tianjin, 300071, China.

まとめ

ミネラルコルチコイド受容体 (MR) 調節は,肥満および高血圧マウスの血管の健康を改善し,オートファギーを減少させた. これはMRIによる血管損傷の 鍵となる要因であることを示唆しています

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