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小児患者の抗吸収治療の前に歯科クリアランスは必要ですか?
Timothy W Neal1, Sayyed Mohseni1, Victoria Ratcliffe1
1Department of Surgery, Division of Oral and Maxillofacial Surgery, UT Southwestern/Parkland Memorial Hospital, Dallas, TX, USA.
Oral surgery, oral medicine, oral pathology and oral radiology
|August 31, 2025
まとめ
抗吸収療法の前に歯のクリアランスを受けた小児患者は,薬剤による骨硬化 (MRONJ) のリスクが増加しなかった. 歯のクリアランスは,より良いフォローアップケアと関連していました.
科学分野:
- 小児歯科
- 口腔医学
- 薬理学について
背景:
- 薬剤による骨死 (MRONJ) は,抗吸収療法の潜在的な合併症である.
- 抗吸収剤を投与する小児患者の治療前の歯のクリアランスの役割は,調査が必要です.
研究 の 目的:
- 治療前の歯のクリアランスとない小児患者のMRONJの発生率を比較する.
- 治療後の歯科フォローアップの頻度に対する歯のクリアランスの影響を評価する.
主な方法:
- 抗吸収剤で治療された小児患者 (< 18歳) の遡及研究 (2010年−2024年).
- 治療前の歯のクリアランスを有する群と無する群の間で,MRONJの発生と歯科訪問の頻度の比較.
主要な成果:
- クリアランス (n=88) またはクリアランスなし (n=48) のグループでは,MRONJの症例は観察されなかった.
- クリアランス群は,クリアランス群 (0. 55) と比較して,治療後の年間平均歯科診察数が著しく高かった (1. 21) (P = . 0002).
結論:
- 治療前の歯のクリアランスは,抗吸収療法を受けている小児患者のMRONJのリスクを増加させるようには見えない.
- 歯のクリアランスは,この集団における継続的な歯科の定期的なフォローアップと関連しています.
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