1990年から2021年までの急性グルメロネフライトの世界的負担と健康格差: 2021年の世界疾病負担研究の体系的分析
Kaixin Lei1, Zibing Zhao2, Ao Chen1
1Department of Nephrology, Kidney Research Institute, West China Hospital of Sichuan University, Chengdu, Sichuan, China.
Renal failure
|August 31, 2025
まとめ
世界的に急性グルメロネフライト (GN) の負担は減少していますが,2040年までに発生率と流行率が上昇すると予測されています. 中央のSDI地域は,特に子供や高齢者が不釣り合いな負担に直面しています.
科学分野:
- 腎臓科
- 流行病学
- 世界保健
背景:
- 急性グルメロネフライト (GN) は,子供および成人のグルメル損傷の重要な原因です.
- 急性GNの全般的な発生率,罹患率,死亡率,およびDALYに関する最近のデータは限られている.
- これらの傾向を理解することは 公衆衛生の介入にとって極めて重要です
研究 の 目的:
- 急性GNの発生率,罹患率,死亡率,およびDALYの最新の世界的な傾向を提示する.
- 急性GNに関連した健康上の不平等を分析する.
- 2040年までに急性GNの将来の傾向を予測する.
主な方法:
- 発生率,流行率,死亡率,および DALY のグローバル,地域,および国内データを活用した.
- 推定年率変化 (EAPC) を用いて分析した傾向.
- 2040年まで予測した年齢,性別,社会人口指数 (SDI) による世界的な傾向を調べた.
主要な成果:
- 2021年,急性GNは,528,368件の発生症例,35,452件の流行症例,10,761件の死亡,および312,303件のDALYをもたらしました.
- 子供 (14歳未満) と高齢者 (85歳以上) が最も重症である.
- 中央のSDI国は,病気の負担を減らすために最大の可能性を示しました.
結論:
- 過去30年間に急性GNの負担が減ったにもかかわらず,人口増加と高齢化により2040年までに発生率と流行率が増加する可能性があります.
- 中部 SDI 地域は急性 GN の不釣り合いの負担を負っています.
- 中級SDI地域では,脆弱な集団,特に子供や高齢者に対して,標的を絞った介入が必要である.
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