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Updated: Sep 9, 2025

Intracellular Phosphoflow Cytometry of Acute Myeloid Leukemia Patient-Derived Xenotransplants
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Intracellular Phosphoflow Cytometry of Acute Myeloid Leukemia Patient-Derived Xenotransplants

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メタボリック酵素の焦点粘着キナーゼ/Srcファミリーキナーゼ軸媒介型チロシン酸化は腫瘍転移を促進する

Jie Chen1,2,3,4, Jing Zhang5,6,7, Yuheng Zhu5,6,7

  • 1Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Laboratory of Molecular Oncology, Peking University Cancer Hospital & Institute, Beijing, China. cj_blue@126.com.

Signal transduction and targeted therapy
|August 31, 2025
PubMed
まとめ

焦点粘着キナーゼ (FAK) /Srcファミリーキナーゼ (SFK) 軸は,細胞代謝を変化させ,食道状細胞癌 (ESCC) の転移を誘導する. この過程を阻害し,転移したESCCを治療する有望な化合物です.

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