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Updated: Sep 9, 2025

The Soft Agar Colony Formation Assay
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新しい小分子はCDK1発現を抑制し,腫瘍特異の細胞の風景を標的として皮膚状細胞がんにおけるWnt/β-カテニンのシグナル伝達を阻害する

Soung-Hoon Lee1, Min-Jeong Kang2, Mi Ryung Roh3

  • 1CK Regeon Inc., Yonsei Engineering Research Park, Yonsei-ro 50, Seodaemoon-gu, Seoul, South Korea. greateondal84@yuhs.ac.

Experimental & molecular medicine
|August 31, 2025
PubMed
まとめ

新しい小分子であるKY19382とKY19334は,Wnt/β-カテニンのシグナル伝達を阻害し,がん細胞の増殖を抑制する. これらの薬剤は,皮膚状細胞癌 (cSCC) およびCDK1過剰発現による他の癌の治療に有望である.

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