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Updated: May 10, 2026

Generation of Human Brain Organoids for Mitochondrial Disease Modeling
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グリオキサラゼ1欠乏によるミトコンドリア機能障害は,ヒトの多能幹細胞の最終的な内皮およびアルベオラの発達を妨げます

Suji Jeong1, Hyebin Koh2,3, Minje Kang1

  • 1Department of Internal Medicine, School of Medicine, Kangwon National University, Chuncheon, Republic of Korea.

Experimental & molecular medicine
|August 31, 2025
PubMed
まとめ

Glyoxalase 1 (GLO1) は,ヒト誘発性多能幹細胞 (hiPS) の決定的な内皮 (DE) への分化に不可欠である. GLO1はミトコンドリア・ホメオスタシスを維持し,DEとアルベオラの発達に不可欠です.

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