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Updated: Jul 8, 2026

SDS-PAGE/Immunoblot Detection of Aβ Multimers in Human Cortical Tissue Homogenates using Antigen-Epitope Retrieval
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脳の脊髄液からβ-アミロイドペプチドを選択的に抽出するためのミニチュア化されたアプタマーベースのモノリシック吸着剤の合成と特徴付け

Israel Donizeti de Souza1,2, Caroline Fernandes Grecco1,2, Maria Eugênia Costa Queiroz2

  • 1Department of Analytical, Bioanalytical Sciences and Miniaturization (LSABM), Chemistry, Biology and Innovation (CBI), UMR 8231 ESPCI Paris - CNRS, ESPCI Paris, PSL University, 10 Rue Vauquelin, 75005, Paris, France.

Analytical and bioanalytical chemistry
|August 31, 2025
PubMed
まとめ

新しい小型化オリゴソーベンツ (mOS) は,アルツハイマー病の診断に重要なバイオマーカーであるβ-アミロイド (Aβ) ペプチド40と42を選択的に抽出します. この進歩により,脳脊髄液の微量分析の精度が向上します.

キーワード:
アミロイドβペプチドアプタマーバイオマーカー脳脊髄液ミニチュア化されたオリゴソーベンツモノライト

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