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Updated: May 12, 2026

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ジャンチン酸化酵素阻害剤アロプリノールは,外周性単神経症のマウスモデルにおける熱的および機械的過敏症を予防する

Aécio C Fagundes1, Gisele Hansel1, Diogo O Souza1

  • 1Departamento de Bioquímica, Instituto de Ciências Básicas da Saúde (ICBS), Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil.

Pharmacological reports : PR
|August 31, 2025
PubMed
まとめ

No abstract available in PubMed .

キーワード:
アデノシンアロプリノールグアノシン痛みを感じるピューリンクサントリン酸化酵素

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Indirect-Acting Cholinergic Agonists: Pharmacological Actions01:30

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Indirect-acting cholinergic agonists, also known as anticholinesterases, exert their pharmacological effects by enhancing cholinergic transmission in various body parts, including the neuromuscular junction, autonomic cholinergic synapses, and the brain.
At the neuromuscular junction, these agents work by inhibiting the breakdown of acetylcholine, allowing it to remain bound to the receptor and bind to nearby receptors. This process leads to repetitive firing of the endplate, causing muscle...